Cialis (Tadalafil) Prices
Cialis (Tadalafil) 20 mg –> from $ 1.05/pill
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Many men associate erectile dysfunction, as well as its main manifestations, with mature age. It is believed that representatives of the stronger sex under 40 years of age have delicate problems extremely rarely. In fact, this is not entirely true, impotence is caused by many factors, which means that it can develop in a man of any age. Cialis potency tablets will help to correct the situation.
The main active ingredient of the drug Cialis is tadalafil, which helps with sexual disorders and impotence in men. The remaining components of the tablets perform auxiliary functions and do not have a therapeutic effect
What is Cialis, and how does it work
Cialis is a drug intended for the treatment of erectile dysfunction and improving erection for full sexual intercourse. The mechanism of action of the drug is the active substance tadalafil, which is a selective inhibitor of specific phosphodiesterase type 5 (PDE5) cyclic guanosine monophosphate (cGMP). Recent studies also show a good potential of tadalafil in the treatment of benign prostatic hyperplasia.
The principle of action of the drug Cialis:
- During sexual arousal, there is a local release of nitric oxide in the blood of the penis.
- The use of tadalafil leads to an increase in the concentration of cGMP in the cavernous bodies of the penis.
- The consequence of this is the relaxation of the smooth muscles of the arteries and improved blood flow to the tissues of the penis.
This allows you to achieve a full and persistent erection.
The effect of the drug lasts up to 36 hours and will be fully revealed only with sexual stimulation; that is, in order to achieve a persistent and long-lasting erection, a man needs to be aroused.
A course of taking pills allows you to significantly correct existing problems, get rid of erectile disorders, and normalize potency.
Indications for use
Male potency is an unstable indicator; in order to always be in “good shape,” it is necessary to monitor your health and nutrition and give up alcohol and nicotine. If this does not help, then start using medication.
Direct indications for prescribing Cialis are considered to be:
- Erectile dysfunction.
- Inability to perform full-fledged sexual intercourse.
- The emergence of problems with potency.
- Violation of blood flow to the organs of the reproductive system.
- Age-related changes that have led to a decrease in libido.
- Erectile dysfunction and its initial signs.
These are the main reasons for starting to take the drug. Cialis can also act as an adjuvant in the treatment of prostatitis and benign prostatic hyperplasia. In this case, the tablets are part of a combination therapy, combined with other drugs.
Method of administration and dosage
The use of tablets, dosage are determined individually by the doctor. It all starts with minimal doses, after which an increase is permissible, but everything depends on how the body reacts to taking the pills.
The instructions for use recommend taking Cialis according to the following scheme:
- For patients with frequent sexual activity (more than 2 – 3 times a week) daily once a day at 5 mg, at the same time. Depending on individual sensitivity to the drug, the dose can be reduced to 2.5 mg.
- If a man is not sexually active with a frequency of less than twice a week, the recommended dosage is 20 mg 15 – 20 minutes before sexual intercourse.
- The maximum daily dose is 20 mg, it is advisable to wash down Cialis with a small amount of liquid, the effect will begin to appear in 15 – 30 minutes.
Cialis can be taken with alcohol, the annotation does not contain any contraindications for their simultaneous use. However, this compatibility is considered relative since the drug affects blood pressure. When combined with large amounts of alcoholic beverages, tadalafil causes side effects, puts stress on the heart and blood vessels, and can cause harm to the body.
With a single dose of 40 mg or more, there is a risk of overdose. Clinical studies have shown that if the dosage is exceeded (single-time), the risk of developing arterial hypertension increases. In this case, symptomatic therapy is carried out.
Cialis main contraindications
Tadalafil, acting as the only active substance in Cialis, determines all contraindications to the use of the drug. Cialis is absolutely contraindicated in the following situations:
- Individual intolerance to tadalafil, allergy to it;
- Taking nitrates (nitroglycerin, isosorbide mononitrate, isosorbide dinitrate, etc.) and nitrate-like agents (molsidomine). These drugs are used for angina (heart pain during physical exertion) and are able to dilate the blood vessels of internal organs. Their side effect is a decrease in blood pressure. Combining these drugs with tadalafil may result in the development of painful, uncontrollable erections or cause a sharp drop in blood pressure, accompanied by dizziness, weakness, nausea, loss of consciousness, and in severe cases, stroke or heart attack;
- Taking alpha-blockers (prazosin, doxazosin). These drugs lower blood pressure by relaxing blood vessels and can improve blood circulation in the male genital organs. In combination with tamsulosin, like nitrates, alpha-blockers can cause uncontrolled erection or lead to a drop in blood pressure.
Relative contraindications include:
- Use in women and individuals under 18 years of age. The effect of the drug in these population groups has not been studied;
- Myocardial infarction suffered within the last 3 months. Physical activity during intimacy can provoke an attack of angina (burning pain in the heart), heart rhythm disturbances, repeated heart attack, and increased blood pressure (BP);
- Unstable angina (newly developed or progressive) or angina during intimacy. As in the previous case, physical activity can cause a heart attack, a jump in blood pressure, and heart rhythm disturbances;
- Heart failure (shortness of breath, swelling in the legs that occur during physical activity). There is a risk of increased symptoms and heart rhythm disorders;
- Heart rhythm disturbances. Intimacy can provoke arrhythmia and lead to blood pressure changes, angina, heart attack, and stroke associated with arrhythmia;
- Uncontrolled low or high blood pressure;
- Stroke in the last six months. There is a risk of a repeated stroke during intimacy;
- Retinal diseases. Due to the fact that tadalafil can affect the activity of PDE located in the retina, its use can lead to unpredictable visual impairment;
- Tendency to uncontrolled erection. Observed in people with mental disorders, oncohematological pathology. The use of Cialis can provoke an erection that is uncontrollable;
- Congenital or acquired deformation of the penis (trauma, surgery, developmental anomalies, Peyronie’s disease). There is a risk of developing painful sensations during erection;
- Severe renal dysfunction. The risk of developing side effects of tadalafil increases.
Neglecting contraindications for the use of Cialis is likely to cause the development of side effects.
The use of the drug in high dosages and incorrect use leads to the risk of unwanted side effects.
What you can not take the tablets with:
- simultaneous use with magnesium preparations reduces the rate of absorption of tadalafil;
- in combination with Acetylsalicylic acid, in case of bleeding, its duration increases;
- enhances the hypotensive effect of nitrates;
- when using blood pressure lowering agents, their dosage should be reduced when taking tadalafil;
- erythromycin, ritonavir, itraconazole, ketaconazole, and saquinavir should be taken with caution;
- a decrease in the plasma level of tadalafil may be observed when taking CYP3 A4 inducers, namely rifampicin.
The effect of Cialis on the heart
Neither Cialis nor any of its generics have a direct effect on the myocardium. All negative effects that may arise from the cardiovascular system in general and the heart in particular are associated with physical activity, which is an integral part of intimacy.
A man who is accustomed to sedentary work, travels by personal transport and has not done any physical exercise for a long time is absolutely not prepared for stress.
Moreover, an untrained organism will poorly tolerate such a very specific activity as sexual intercourse, especially considering that after taking tadalafil, a man will decide that all his youthful strength and agility have returned to him.
It is quite natural that taking any potency regulator, it does not necessarily have to be Cialis, the heart will give the maximum possible frequency of contractions and the height of blood pressure. How dire the consequences of such “exercises” will be depends only on whether there are chronic diseases in the form of hypertension, atherosclerosis (cholesterol deposition on the walls of the arteries), and other factors.
Hypertensive crises, heart attacks, rhythm disruptions, and strokes against the background of intimacy are quite common cases in the practice of doctors of various specialties.
Side effects
The male body reacts differently to taking certain medications. At the same time, each system of the body signals a malfunction in its own way. As for the use of Tadalafil, many men often complain of facial swelling, slight absent-mindedness and fatigue, as well as asthenia and pain in different parts of the body.
Let’s consider how each of the body’s systems reacts to the drug.
- From the gastrointestinal tract, there is a change in the results of liver tests, a sharp increase in gamma-glutamyl transpeptidase, and such diseases as dysphagia, esophagitis and gastroesophageal reflux were diagnosed. Most often, patients showed such ailments as abdominal pain, diarrhea, nausea and vomiting.
- From the cardiovascular system, the reaction was in the form of tachycardia, rapid heartbeat, chest pain, angina. Also, sharp jumps in blood pressure were recorded in men. Experts also talk about the high risk of myocardial infarction.
- From the side of the central nervous system, side effects were noted in the form of hypoesthesia, insomnia, vertigo, and increased drowsiness.
- From the side of the musculoskeletal system, side effects were manifested in the form of pain symptoms in the lumbar region, neck, and limbs.
- From the respiratory system, taking generics can cause dyspnea, nosebleeds, and pharyngitis.
- From the side of vision, side effects in men can manifest themselves in the form of a short-term change in color rendering, swelling of the eyelids, pain in the eyes, and increased lacrimation.
- In rare cases, use of the drug can cause skin rash, increased sweating, burning or itching in certain areas of the body.
- From the side of the genitourinary system, undesirable side effects should be noted as spontaneous uncontrolled erection, which occurs for no apparent reason. The fact is that the occurrence of a natural and persistent erection at the moment of sexual intimacy with a partner is a normal effect of taking the drug, whereas the spontaneous onset of an erection is actually a side effect.
Cialis and alcohol: drug compatibility
Men take a small amount of alcohol while taking Cialis in order to reduce neuromuscular tension. The active substance of the drug is tadalafil. It does not have molecules in its structure that would interact with ethanol. The instructions for the drug indicate that the drug can be combined with food or a small amount of alcoholic beverages.
But in the case of alcoholism, the drug is contraindicated. This is not due to the components or action of Cialis but to a metabolic disorder.
Side effects occur with alcohol addiction when large amounts of alcohol are consumed. This occurs due to liver dysfunction. The organ carries out biochemical reactions of breaking down substances that enter the human body. Cialis is also biotransformed in the liver. A large amount of ethyl in the blood leads to a slowdown in the elimination of the drug from the body.
During a course of treatment, when it is time to take the next dose of the drug, the previously taken Cialis has not yet been completely eliminated. As a result, the concentration of the active substance is higher than permissible, which increases the risk of complications from the cardiovascular system.
The compatibility of Cialis and alcohol does not cause intoxication syndrome. It occurs with alcohol abuse or alcoholism due to a decrease in the detoxification function. Alcohol in moderate quantities promotes relaxation and increases sexual desire, and taking the drug provides a stable erection.
When consuming low-quality alcohol and large quantities of strong drinks, the centers of the medulla oblongata and erectile dysfunction are suppressed. Taking a stimulant does not have the desired effect.
Complications of the interaction of the stimulant and ethanol are acute ischemic attacks and sudden death syndrome. Uncontrolled intake and combination of the drug and ethanol are especially dangerous. This increases the risk of myocardial infarction, stroke, paroxysmal tachycardia, and other arrhythmias.
If you take the medicine correctly, do not exceed the dosage, and consult a doctor, then you can use Cialis for a long period of time. A course of treatment will allow you to achieve good results, achieve a stable erection, have a full act, and get maximum pleasure from intercourse.
Final thoughts
Cialis has proven to be an effective medication for the treatment of erectile dysfunction, offering men a reliable way to enhance their sexual performance and confidence.
With tadalafil as its active ingredient, Cialis works by improving blood flow to the penis, ensuring a firm and lasting erection when combined with sexual stimulation. Its long duration of action, up to 36 hours, makes it a preferred choice for many.
However, like any medication, Cialis must be used responsibly. Understanding its dosage, potential side effects, and contraindications is crucial to avoiding complications. Special care should be taken when combining the drug with alcohol or other medications, as this may increase health risks.
Consulting a healthcare provider before use is highly recommended, especially for individuals with pre-existing cardiovascular conditions or those taking other prescription drugs.
By following medical advice and using Cialis correctly, men can safely restore their sexual function and improve their overall quality of life.